Hitting the Target in HER2-Positive Metastatic Colorectal Cancer
STATEMENT OF NEED
An estimated 153,020 new cases of colorectal cancer (CRC) are diagnosed annually, and 52,550 people die of the disease (Siegel et al, 2023). Approximately 22% of patients present with metastatic disease, which is associated with a dismal 5-year survival rate of 15% (SEER, 2022). Targeting biomarkers is a key strategy for expanding therapeutic options and improving outcomes in metastatic CRC. Human epidermal growth factor receptor 2 (HER2) amplification status and treatment... |
|
Cushing’s Disease Research Highlights: ENDO 2023
This 30-minute CME program highlights the latest clinical research about Cushing’s disease.
Cushing’s disease is caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary tumor that leads to excessive levels of cortisol.
This CME program, hosted by Lisa Machtigall, MD, Clinical Director, Neuroendocrine & Pituitary Tumor Clinical Center at Massachusetts General Hospital, and Associate Professor of Medicine at Harvard Medical School, provides an overview of the latest cli... |
|
|
Ace the Case: A 65-Year-Old Woman With Chronic Diabetic Macular Edema in Both Eyes
In this clinical case review, Dr. Sara Haug explores considerations for the management of a patient with DME who is receiving monthly anti-VEGF therapy without attaining disease control. |
|
Pathways for Optimal Sequencing, Rapid Initiation, and Titration of Therapy in Patients with Heart Failure
Many patients with heart failure (HF) do not receive foundational treatment although these therapies reduce morbidity and mortality risks. The initiation and optimization of guideline-directed medical therapies (GDMT) can be challenging, but clinical practice guidelines and algorithms are available to assist.
Navigate through this interactive self-directed CME activity to apply the most recent clinical trial data and guidance to patient-specific factors seen in real-world practice. Expert p... |
|
Call to Action for Health Equity: Racial Disparities in the Care of Patients with Cardiometabolic Disease
Cardiovascular disease is the leading cause of death for adults in the US. However, patients from minority populations with cardiovascular disease have disproportionately poor health outcomes and are particularly vulnerable to health disparities. Racial inequities in health also result in higher risk-burden in minority groups for metabolic syndromes such as Type 2 (adult-onset) diabetes, which increase the risk of cardiovascular disease. Health disparities in cardiometabolic care predominantly... |
|
Applying Guidelines and Latest Evidence to the Management of Moderate‐to‐Severe Asthma in Children and Adults
Target Audience
The educational design of this activity addresses the needs of pulmonologists, allergists/immunologists, NPs and PAs, and other clinicians involved in the management of patients with moderate‐to‐severe asthma.
Program Overview
Patients with asthma and underlying comorbidities require personalized treatment to achieve asthma control. Children with asthma have an especially high burden of symptoms, and are at risk of impaired lung development if asthma control cannot be ... |
|
Contemporary Management of Patients with Systemic Lupus Erythematosus: A Case-based Approac
This modular continuing education activity provides an update on the epidemiology, monitoring, and treatment of patients with systemic lupus erythematosus (SLE). Diane Kamen, MD, and Anca Askanase, MD, examine the current research on demographic groups with an increased risk of SLE and its severe complications, including lupus nephritis (LN). They also review the application of the most current treatment goals and classification criteria to speed diagnosis and guide disease activity monitorin... |
|
Hot Topics in Blood-based Cancer Screening: Key Information on Multi-Cancer Early Detection from 2023 Spring Oncology Meetings
Early detection of cancer is essential to reducing the significant burdens associated with it. When cancer is detected at earlier stages, treatments can be initiated sooner, resulting in improved outcomes, reduced morbidity and mortality, and better quality of life. While the implementation of current screening guidelines has resulted in an overall reduction in cancer deaths, only 25% of cancers are diagnosed using traditional screening modalities, leaving much room for improvement. Blood-base... |
|
Cardiovascular Considerations in COPD Management
With cardiovascular disease coexisting in up to 60% of COPD cases, optimal management of each disease is imperative to successful patient outcomes. In this Phone-a-Friend episode, Dr. MeiLan Han consults with Dr. Ty Gluckman to discuss a patient with a 5-year history of COPD and cardiovascular risk factors that may be contributing to his persistent symptoms. |
|
Clinical Updates in Chronic Graft-versus-Host Disease and Applications for Academic and Community Practice
Target Audience
The target audience for this activity are hematologists, oncologists, immunologists, and bone-marrow transplant specialists.
Program Overview
Chronic graft-versus-host disease (cGvHD) is a common, multi-symptom complication of allogeneic transplantation that severely affects patient well-being. While the medical systems and resources differ between academic and community healthcare settings, clinicians practicing in both environments would benefit from education about rece... |
|
Cleveland Clinic 13th Annual Neurology Update
Cleveland Clinic’s 13th Annual Neurology Update features a faculty of more than a dozen thought leaders discussing the most current clinically focused information regarding diagnosis, medication and therapy for a wide variety of neurologic conditions. This comprehensive review will detail strategies, procedures and best practices throughout the specialty. Neurologists, general practitioners, nurses and physician assistants will all benefit from the latest information impacting the practice... |
|
LET'S TALK: Tackling Complex Issues Regarding SM-AHN Management A Monday Morning Joe Online Educational Activity
Systemic mastocytosis (SM) is a group of rare disorders characterized by the accumulation of mast cells in internal tissues and organs. The pathogenesis of SM is linked to a characteristic exon 17 D816V mutation of the KIT gene. Systemic mastocytosis with associated hematologic neoplasms (SM-AHN) is an advanced subtype of SM that is associated with a shortened median survival time. Recent advances in the SM therapeutic landscape have led to the development of KIT-targeted treatment options; ho... |
|
Promoting Equitable Oral Health in Patients of Color
There are many vulnerable and underserved populations in oral health. Gaps in health and health care are often caused by the disconnect between medical and dental care and a fragmented system that has left 74 million people without dental insurance, leading to knowledge gaps and a lack of dental-medical collaboration and coordination in patient care. These issues are exacerbated in patients of color, often due to interpersonal racism.
This CME Outfitters BriefCase will feature patient case ... |
|
Irregular Care: Racial Inequities in the Management of Cardiac Rhythm Disorders
Structural racism and classism leads to many of the social determinants of health (SDoH) that cause disparities in cardiovascular (CVD) care, such as unequal preventative care, heart arrythmia treatment, and research inclusion. Interpersonal racism, including unconscious bias, worsens disproportionate CVD care, and is also a stand-alone factor for this health inequity. Underrepresented minority (URM) patients – particularly Black/African American individuals – are less likely to receive, b... |
|
Managing Opioid Misuse Disorder in Pregnancy and Neonatal Care
This course familiarizes physicians with evaluation and treatment of patients who present with maternal opioid use during and after pregnancy.
Outcome Objectives:
As a result of completing this activity, the participant will be better able to:
- Identify the specific problems encountered by women using opioids during pregnancy
- Evaluate pregnant patients with a history of maternal opioid use
- Differentiate between maintenance options for opioid treatment during pregnancy
- Assess... |
|
Are You Seeing the Whole Picture? Test Your Skills for Intensifying Therapy in Patients with Type 2 Diabetes
The management of type 2 diabetes (T2D) has evolved rapidly with new agents and changing recommendations. Do you see the whole picture when selecting therapy for your patients? Engage in this interactive clinical case challenge to see whether your treatment selection aligns with guideline recommendations and account for cardiovascular disease risks, patient-centric factors, and weight management. |
|
Delivering Culturally Competent Care: Managing Type 2 Diabetes in Diverse Populations
This course presents practical advice for working cross-culturally. It allows participants to practice and improve their communication skills while managing typical clinical problems encountered in persons with type 2 diabetes.
Outcome Objectives:
As a result of completing this activity, the participant will be better able to:
- Recognize the differences between the terms "race," "ethnicity," and "culture."
- Employ the Ask, Share, Compare, Negotiate Model with patients in the office... |
|
Thymidine Kinase 2 Deficiency: From Diagnostic Odyssey to Timely Diagnosis and Treatment
Mary Kay Koenig, MD, a leader in the management of patients with mitochondrial diseases, delves into the complexities of managing patients with thymidine kinase 2 deficiency (TK2d). In this 1-hour activity, Dr. Koenig shares her insights in the clinical presentation of TK2d through real case studies and offers guidance on overcoming the ‘diagnostic odyssey’ experienced by many patients with mitochondrial disease. She also discusses the clinical criteria for referring patients to specialize... |
|
Therapeutic Advancements for the Treatment of High-Risk MDS: Future Opportunities to Improve Patient Survival and Quality of Life
Stay up to date on the evolving risk classification for myelodysplastic syndromes (MDS) and current treatment guidelines for patients with high-risk disease in this self-directed education with leading oncology experts. Expert commentary from Courtney DiNardo, MD from MD Anderson Cancer Center and Dr. Dan Pollyea from the University of Colorado School of Medicine provides insights on emerging therapies that could soon improve management of high-risk MDS. Be ready to incorporate these emerging ... |
|
Making the Case to Use JAK Inhibitors for Rheumatoid Arthritis"Who, What, When, and How
Target Audience
This activity has been designed to address the educational needs of rheumatology clinicians. It may also benefit other clinicians involved in the management of patients with rheumatoid arthritis (RA).
Program Overview
Join Dr Rigby and Dr Troum as they discuss the use of Janus kinase (JAK) inhibitors for the treatment of RA. In this program they will discuss the latest post-hoc analysis of the ORAL Surveillance trial, which shows which patients can safely and effectively u... |
|
Case Studies in HIV Resistance Testing and Treatment " Experienced Patients
Educational Need:
Through a series of patient cases, participants will explore the complexities of managing HIV infection in patients who have been treated with multiple different HIV regimens. Participants will engage in real-life case studies that will provide valuable insight into the intricacies of HIV treatment and resistance testing. Our faculty educators will discuss commonly encountered challenges faced by the care team and their treatment-experienced patients with HIV and offer real... |
|
Clinical Questions in Cardiology: Using Glucagon-like Peptite-1 Receptor Agonists
The glucagon-like peptide-1 receptor agonist (GLP-1RA) class of medications has become an important option for treating patients with type 2 diabetes mellitus (T2D). Cardiovascular outcome trials also show that selected GLP-1RAs exert beneficial cardiovascular benefits in patients with and without T2D. In this activity, case studies commonly encountered in cardiology practice are utilized to prompt reflection on opportunities for reducing cardiovascular risk. Drawing on seminal research and th... |
|
Addressing Key Questions About BCMA-Targeted Therapy for Relapsed/Refractory Multiple Myeloma
ACTIVITY DESCRIPTION
Though treatment advances have improved outcomes for most patients, MM remains an incurable disease characterized by continuous relapse. However, the treatment landscape for relapsed/refractory MM (RRMM) has expanded in recent years, and patients who relapse and/or become refractory to initial therapies are benefiting from the increasing availability of a diverse range of novel agents, including B-cell maturation antigen (BCMA)"targeted immunotherapies. These agents ... |
|
Raising the Bar in ATTR Amyloidosis A Training Set on Diagnosis and Treatment
There is considerable heterogeneity in the clinical manifestations of ATTR amyloidosis, which are often dependent on both genetic and environmental factors. Once a fatal diagnosis with no effective therapies available, research in ATTR amyloidosis is rapidly evolving and new pharmacotherapies that demonstrate improved quality of life and life expectancy for patients have been developed. Despite this progress, treatment options remain limited, underscoring the need to continue to expand the tre... |
|
Cleveland Clinic 27th Annual Diabetes Therapeutics, Technology and Surgery (Online Streaming On Demand)
For over a quarter century, Cleveland Clinic has been at the forefront of continuing education regarding the treatment and management of diabetes. Its world class faculty has designed the 27th Annual Diabetes Therapeutics, Technology and Surgery to provide up-to-date reviews of strategies and research relevant to this disease and its complications. The goal of this activity is to increase practitioners’ competence and clinical performance in the management of type 1 and type 2 diabetes. A... |
|
Cleveland Clinic Primary Care + (online streaming & flash drive formats)
Cleveland Clinic Primary Care + highlights the latest therapies, procedures and diagnostics in primary care, women’s health and behavioral medicine. This best practices review addresses the educational needs of primary care clinicians who must stay abreast of current research and treatments in a wide range of disciplines. Physicians, nurses and physician assistants will all benefit from Cleveland Clinic’s expert analysis of essential subjects in primary care.
Worth 21 AMA PRA Catego... |
|
Ethics for Occupational Therapists
Ethics for Occupational Therapists is a text-based, 3-hour online continuing education (CE/CEU) course that teaches OTs how to address ethical and moral dilemmas in practice.
Ethical and moral issues pervade our lives and healthcare professionals are constantly confronted with a variety of ethical and moral dilemmas. Decisions can have long-range effects professionally and personally, not only for the healthcare professional, but for patients, clients, healthcare entities, and society. Why ... |
|
Suicide Prevention: Evidence-Based Strategies
Suicide Prevention: Evidence-Based Strategies is a 3-hour online continuing education (CE) course that reviews evidence-based research and offers strategies for screening, assessment, treatment, and prevention of suicide in both adolescents and adults.
The Centers for Disease Control and Prevention (CDC) notes, “Suicide is a serious but preventable public health problem that can have lasting harmful effects on individuals, families, and communities.” The CDC recommends a public health a... |